NITRO Studio runs on BOTH SharePoint on-premises and Office 365! NITRO Studio runs on SharePoint 2013, 2016, and 2019 and in Office 365. Microsoft’s Power Platform does not run directly on SharePoint on-premises. It requires a standalone Power Apps subscription (over and above the cost of Office 365) with a Data Gateway to connect to SharePoint on-premises data. This extra subscription runs $10/user/month for one App or $40/user/month for unlimited apps.